Our services provide insight into the immune responses of an individual or a population against specific pathogen proteins or vaccine components.
With an unbiased approach, we can support researchers with:
Our diverse and complementary autoantibody detection products will uncover molecular targets and patterns of reactivity associated with autoimmune diseases, such as lupus, multiple sclerosis, scleroderma, etc.
We can help you understand the specific immune targets within the body’s own tissues, which underly the mechanisms of these diseases.
Antibody reactome profiling will play a prominent role in the next generation of vaccine development by helping to identify key epitopes and revealing crucial mechanistic correlates of vaccine efficacy.
Take an unbiased approach to characterizing allergic antibodies, including food allergies and environmental allergies (e.g., pollen, dust mites). We empower researchers to understand and characterize the specific allergens – at epitope resolution – involved in immune reactions, identifying biomarkers to improve diagnostic and therapeutic strategies.
Antibody reactome profiling can be utilized in the field of cancer immunotherapy to assess the immune response against cancer cells. Take an unbiased approach to identifying tumor-specific antibodies and evaluating the efficacy of immunotherapeutic interventions, such as immune checkpoint inhibitors or monoclonal antibodies. Undesirable immune-related adverse events (irAEs) can also be detected and characterized by antibody profiling.
Let Infinity Bio help you discover novel therapeutic targets or biomarkers associated with various diseases. By analyzing the antibody profiles of patients with specific conditions, you can discover reactivity patterns or specific antibodies associated with disease presence, initiation, progression, modulation, or protection. Better patient stratification will lead to more targeted and effective treatment approaches.
Deeply characterizing each individual’s unique antibody reactome will become a critical component of precision medicine. Gene therapies, microbiome therapies, immunomodulatory therapies – all stand to benefit from a better understanding of each patient’s unique exposure history and immune profile.
Emerging infectious diseases repeatedly threaten global health. Many viruses with pandemic potential circulate in animal reservoirs and several are transmitted by arthropod vectors. In recent decades, global health organizations have emphasized the importance of surveillance for emerging viruses alongside the development of countermeasures, such as vaccines, to mitigate the impact of outbreaks.
